What is Zohydro Addiction?
Discover the impact of Zohydro addiction and find help! Uncover treatment options and resources for individuals struggling with addiction.
Dr. Deyhimy MD
April 28, 2024
Discover the impact of Zohydro addiction and find help! Uncover treatment options and resources for individuals struggling with addiction.
Zohydro addiction refers to the misuse and dependency on the opioid drug Zohydro. Zohydro is made from morphine, which is a natural substance extracted from the seed pod of various opium poppy plants [1]. It is important to recognize the risks associated with Zohydro addiction and the potential consequences it can have on individuals.
Zohydro is a prescription medication used to manage severe pain in cases where alternative treatments are inadequate. It contains hydrocodone, a potent opioid analgesic that provides relief by binding to opioid receptors in the brain and spinal cord. Zohydro is an extended-release formulation, which means it releases the medication over an extended period, providing long-lasting pain relief.
Using Zohydro in a manner not prescribed by a healthcare professional can lead to addiction. Zohydro addiction falls into the category of drugs with the potential for misuse or addiction, as highlighted in the list of commonly used drugs with addiction potential on the NIDA website. When taken nonmedically, Zohydro has the potential to cause euphoria, which can contribute to its addictive nature.
The impact of Zohydro addiction can extend beyond the individual's well-being and affect their overall health. Misuse of Zohydro can lead to health risks such as drugged driving, infectious diseases, and adverse effects on pregnancy. It is crucial to recognize the signs of Zohydro addiction and seek appropriate help and treatment.
It's important to note that Zohydro addiction can result in opioid use disorder, which may require professional treatment. For information about treatment options for substance use disorders, refer to NIDA's Treatment pages [1]. With proper support and intervention, individuals struggling with Zohydro addiction can find the necessary resources and assistance to overcome their addiction and improve their overall well-being.
Zohydro addiction can have significant impacts on both physical and mental health. Understanding the health risks associated with Zohydro misuse and the consequences of addiction is crucial in addressing this issue.
Zohydro, an opioid drug derived from morphine, has the potential for misuse and addiction, as highlighted by the National Institute on Drug Abuse (NIDA). Misusing Zohydro can result in various health risks, including:
Addiction to Zohydro can have severe consequences on the individual's overall well-being and quality of life. Some of the consequences associated with Zohydro addiction include:
Recognizing the health risks and consequences associated with Zohydro addiction highlights the urgency of seeking help and implementing effective prevention and intervention strategies. Treatment options for opioid use disorder are available, and resources are provided by organizations like NIDA to support individuals struggling with Zohydro addiction. By addressing this issue with compassion and appropriate support, individuals can find the necessary help to overcome Zohydro addiction and regain control of their lives.
When dealing with Zohydro addiction, it is crucial to seek appropriate help and support. Overcoming addiction requires a comprehensive approach that addresses the physical, psychological, and social aspects of opioid use disorder. There are various treatment options available and resources to assist individuals struggling with Zohydro addiction.
Treating opioid use disorder, including Zohydro addiction, often involves a combination of medication-assisted treatment (MAT), counseling, and behavioral therapies. MAT utilizes medications to help manage withdrawal symptoms and cravings while reducing the risk of relapse. According to the National Institute on Drug Abuse (NIDA), medications commonly prescribed for opioid use disorder include:
MedicationDescriptionMethadoneA long-acting opioid agonist that helps reduce withdrawal symptoms and cravings. It is typically dispensed through specialized treatment centers.BuprenorphineA partial opioid agonist that can be prescribed by qualified healthcare providers in various settings, including office-based settings.NaltrexoneAn opioid antagonist that blocks the effects of opioids and reduces cravings. It can be administered orally or through an extended-release injection.
These medications work by stabilizing brain chemistry, reducing withdrawal symptoms, and normalizing bodily functions. They can be used as part of a comprehensive treatment plan to help individuals overcome Zohydro addiction. It's important to consult with a healthcare professional to determine the most appropriate medication and dosage for each individual's specific needs.
There are numerous resources available to support individuals struggling with Zohydro addiction and opioid use disorder. Organizations such as the National Institute on Drug Abuse (NIDA) provide valuable information, research, and treatment resources for substance use disorders, including Zohydro addiction. Their website offers comprehensive information on treatment approaches, medications, and counseling options.
In addition to national resources, it is important to consider local resources and support networks. Government agencies, community organizations, and healthcare providers can provide information on local treatment centers, support groups, and counseling services. The Government of Canada, for example, offers culturally sensitive resources through programs such as the National Native Alcohol and Drug Abuse Program and the National Youth Solvent Abuse Program, specifically designed to support First Nation, Inuit, or Métis individuals in need of help with substance use [2].
Seeking help is a crucial step towards recovery from Zohydro addiction. By utilizing available treatment options and resources, individuals can access the support and guidance needed to overcome addiction and regain control of their lives.
Understanding the factors that contribute to Zohydro addiction is crucial in addressing the opioid addiction epidemic. Two key factors that have played a significant role in the rise of Zohydro addiction are the FDA approval process and the increase in opioid prescriptions.
Zohydro, a single-entity, long-acting hydrocodone product developed by Zogenix, received FDA approval on October 25, 2013. However, the approval process itself faced controversy. The FDA's own scientific advisory panel voted 11 to 2 against approving Zohydro, yet it was still approved [3]. This decision raised concerns among various groups, including consumer safety organizations, health care agencies, addiction treatment providers, professional organizations, the US Congress, and state attorneys general.
One of the primary concerns surrounding Zohydro is its highly addictive nature. Hydrocodone, the active ingredient in Zohydro, is a potent opioid that can lead to physical dependence and addiction. The availability of a long-acting formulation like Zohydro increases the risk of misuse and addiction. Critics argue that the approval of Zohydro may have contributed to the ongoing opioid addiction epidemic.
Over the past 15 years, the United States has consumed a significant portion of the global oxycodone and hydrocodone supply. In fact, the US has consumed more than 84% of the global oxycodone and over 99% of the hydrocodone supply. This surge in opioid prescriptions has contributed to the increase in opioid addiction, overdose deaths, and related health consequences.
The rise in opioid prescriptions has surpassed motor vehicle injuries in the US, highlighting the magnitude of the problem. Despite multiple regulations enforced by various organizations, studies indicate that the continued increase in medical use of opioid analgesics from 2000 to 2011 has contributed to the growing misuse and its associated health consequences [3].
These statistics emphasize the need to address the factors contributing to the opioid addiction epidemic, including the responsible prescribing and use of opioids like Zohydro. It is essential for healthcare professionals, policymakers, and organizations to work together to develop strategies that prioritize patient safety and reduce the risk of addiction and misuse.
Opioid addiction is a significant public health concern, and understanding its nature is crucial in addressing the issue effectively. This section explores the understanding of opioid addiction and various prevention and intervention strategies.
Opioids, including Zohydro, can cause euphoria and are often used nonmedically, leading to overdose deaths. Opioid addiction occurs when repeated use of opioids leads to changes in the brain that result in dependence and cravings for the drugs.
Several factors contribute to the development of opioid addiction. According to the American Society of Anesthesiologists, even short-term opioid use can lead to addiction and overdose, with an average of 90 people dying in the U.S. every day due to misuse of opioids. Women are more likely than men to be prescribed opioid medicines, given higher doses, and use opioids for longer periods, which increases their risk of developing opioid use disorder. Taking opioids for more than a few days significantly increases the risk of long-term use and the likelihood of developing an addiction. Even after just five days of taking an opioid medicine, there is an increased chance of still using opioids a year later.
Preventing opioid misuse and addressing opioid addiction requires a multi-faceted approach. Here are some prevention and intervention strategies that can help:
By implementing these prevention and intervention strategies, communities can work towards reducing the prevalence of opioid addiction and promoting healthier alternatives for pain management.
It is important to remember that addressing opioid addiction requires a comprehensive and compassionate approach. Combining education, prevention efforts, and access to treatment and support can make a significant impact in supporting individuals affected by opioid addiction and preventing future cases of misuse.
Zohydro, a single-entity, long-acting hydrocodone product developed by Zogenix in San Diego, has been surrounded by controversies since its approval by the FDA on October 25, 2013. The approval came despite the FDA's own scientific advisory panel voting 11 to 2 against its approval. Various groups, including consumer safety organizations, healthcare agencies, addiction treatment providers, professional organizations, the US Congress, and state attorneys general, have expressed concerns about Zohydro and its potential contribution to the opioid addiction epidemic.
The FDA's decision to approve Zohydro despite the concerns raised by its own advisory panel has sparked controversy. Critics argue that the approval may have disregarded the potential risks associated with the drug, including its high addictive potential. This controversy has led to discussions about the FDA's decision-making process and the need for more rigorous evaluations of medications with opioid properties.
Another point of contention surrounding Zohydro is its efficacy and clinical relevance. Evidence presented to the FDA, based on a study submitted by the manufacturers, showed that only 48% of the patients in the treatment group and 21% of the patients in the placebo group experienced a 50% pain improvement at an 85-day follow-up. The clinical relevance of this statistically significant result remains unknown, raising concerns about the clinical efficacy of the drug.
Critics argue that the potential benefits of Zohydro may not outweigh the risks associated with its use, particularly considering the availability of alternative pain management options. The debate surrounding the efficacy and clinical relevance of Zohydro highlights the need for further research and evaluation to ensure the safe and appropriate use of opioid medications.
By addressing the controversies surrounding Zohydro, it is possible to shed light on the concerns raised by various stakeholders regarding its approval and clinical relevance. These discussions contribute to the ongoing efforts to improve the safety and effectiveness of opioid medications while addressing the challenges posed by the opioid addiction epidemic.
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Dr. David Deyhimy, with over 20 years of experience, is a board-certified physician in addiction medicine and anesthesiology based in Orange County.
Don’t hesitate to contact us today with any questions you may have about our program or if someone you know is struggling with addiction.
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